Protective HIV-specific CD8+ T cells evade Treg cell suppression

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Nature Medicine . 2011 July; 17

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection

Shokrollah Elahi, Toshiro Niki, Mitsuomi Hirashima, Helen Horton

Blood. 2012 May; 119 (18):4192-4204. 10.1182/blood-2011-11-389585

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection

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Nature. 2013 November; 504

Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors

Okoye I., Xu L., Motamedi M., Parashar P., Walker J.W., Elahi S.

Journal for Immunotherapy of Cancer . 2020 December; 8 (2) 10.1136/jitc-2020-001849

Expanded antigen-experienced CD160+CD8+effector T cells exhibit impaired effector functions in chronic lymphocytic leukemia

Bozorgmehr N., Okoye I., Oyegbami O., Xu L., Fontaine A., Cox-Kennett N., Larratt L.M., Hnatiuk M., Fagarasanu A., Brandwein J., Peters A.C., Elahi S.

Journal for Immunotherapy of Cancer . 2021 April; 9 (4) 10.1136/jitc-2020-002189

Galectin-9, a player in cytokine release syndrome and a surrogate diagnostic biomarker in SARS-CoV-2 infection

Bozorgmehr N., Mashhouri S., Rosero E.P., Xu L., Shahbaz S., Sligl W., Osman M., Kutsogiannis D.J., Macintyre E., O’neil C.R., Elahi S.

mBio. 2021 April; 12 (3) 10.1128/mBio.00384-21

Differential transcriptional and functional properties of regulatory T cells in HIV-infected individuals on antiretroviral therapy and long-term non-progressors

Clinical and Translational Immunology. 2021 May; 10 (5):e1289 https://doi.org/10.1002/cti2.1289

Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2

Shahbaz S., Xu L., Osman M., Sligl W., Shields J., Joyce M., Tyrrell D.L., Oyegbami O., Elahi S.

Stem Cell Reports . 2021 May; 16 (5):1165-1181 10.1016/j.stemcr.2021.04.001

The quality of sars-cov-2-specific t cell functions differs in patients with mild/moderate versus severe disease, and t cells expressing coinhibitory receptors are highly activated

Shahbaz S., Xu L., Sligl W., Osman M., Bozorgmehr N., Mashhouri S., Redmond D., Rosero E.P., Walker J., Elahi S.

The Journal of Immunology. 2021 August; 207 (4):1099-1111 10.4049/jimmunol.2100446

Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection

Dunsmore G., Rosero E.P., Shahbaz S., Santer D.M., Jovel J., Lacy P., Houston S., Elahi S.

PLOS BIOLOGY. 2021 August; 19 (8) 10.1371/journal.pbio.3001387

Hematopoietic responses to SARS-CoV-2 infection

Elahi S.

Cellular and Molecular life Sciences . 2022 March; 79 (3) 10.1007/s00018-022-04220-6

Elevated ATP via enhanced miRNA-30b, 30c, and 30e downregulates the expression of CD73 in CD8+T cells of HIV-infected individuals

Shahbaz S., Okoye I., Blevins G., Elahi S.

PLoS Pathogens. 2022 March; 18 (3) 10.1371/journal.ppat.1010378